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WILLIS
LAW FIRM

5252 Westchester St.
Suite #275
Houston,Tx 77005

TOLL FREE
1-800-883-9858
1-800-468-4878


Legal Assistance for PPH & Diet Drug Victims since 1997  

Ephedra - PPH Connection

Can Ephedra (Ma Huang) Cause Primary Pulmonary Hypertension (PPH) ? Do the Ephedrine Alkaloids from Dietary, Nutritional and Herbal Supplements Have a Causal Link to PPH ?   Primary pulmonary hypertension (PPH) is a rare and often fatal disease that results in the progressive narrowing of the blood vessels of the lungs which as a result causes high blood pressure in these blood vessels and eventually leads to heart failure. The lungs contain millions of tiny blood vessels called capillaries. These capillaries are extremely small, just wide enough for blood cells to move through.ephedra,PPH,cause,primary pulmonary hypertension,ephedra, phentermine, ephedra,PPH, ephedrine,ma huang, does ephedra cause pph, metabolife pph,pulmonary hypertension,pph causes, fastin, cause,dietary,amphetamine,nutritional herbal,supplements,link,medical,legal,lawyer The capillaries are lined with endothelial cells that prevent blood from leaking out of the vessel. The outside of the blood vessels are muscle type cells that expand and contract as blood moves through from the heart into the lungs. PPH causes the cell lining of the lung's blood vessels to weaken and allow leakage. The leaking of blood out of the vessels causes the muscles that surround the blood vessels to constrict. This continuous constriction increases the pressure within the blood vessels and cuts off blood flow. The constriction gradually worsens, eventually increasing the pulmonary arterial pressure. Secondary pulmonary hypertension (SPH) is the result of other types of lung disease, abnormal breathing processes or heart disease.

      No one is certain as to what  the exact causes primary pulmonary hypertension (PPH), but research has shown that there are a number of factors that may be responsible for the disease. Some of the possible causes include immune system disease, congenital heart defects, portal hypertension, HIV infection, Collagen Vascular Disease, amphetamine use, and intravenous drug use  or other chemical exposures. The use of certain appetite suppressants, such as Pondimin (fenfluramine) and  Redux (dexfenfluramine), have been found to greatly increase the risk of developing PPH.  

 SYMPTOMS OF PRIMARY PULMONARY HYPERTENSION (PPH)

  • Shortness of breath following exertion,
  • Excessive Fatigue,
  • Ankle Swelling,
  • Bluish Lips and skin
  • Fainting, and/or
  • Chest pain
Is Ephedra the type of amphetamine like compound that can cause Primary Pulmonary Hypertension (PPH) ?

Ephedrine (e-fed-rin) a-methylamino-l phenyl-l propanol, is an alkaloid from the leaves of Ephededra equisetina, E. Sinica, and other species  (family Gnetaceae) It is also called Ephedra & Ma Huang, the plant source   for the Alkaloid ephedrine.  Indigenous to China, India and parts of South East Asia. Theses are amphetamine-like compounds with powerful and potentially lethal stimulant effects on the central nervous system and the heart. Research is underway that may show a link to ephedra ( ephedrine alkaloids)  and primary pulmonary hypertension. Between 1967 and 1973, a 10-fold increase in unexplained pulmonary hypertension was reported in central Europe. The rise was subsequently traced to aminorex fumarate, an amphetamine-like drug introduced in Europe in 1965 to control appetite. Only about 1 in 1,000 people who took the drug developed PPH. When they stopped taking the drug, some improved considerably; in others, the disease kept getting worse. Once aminorex was removed from the market, the incidence of PPH went down to normal levels.

Primary Pulmonary Hypertension (PPH) Risk Factors

Taken from the World Health Organization executive summary, the following risk factors have been categorized based on the strength of the association with PPH and their probable causal role. "Definite" indicates an association based on several concordant observations, including a major controlled study or a clear epidemic. Definite risk factors are considered to play a causal role in the development of the disease. "Very likely" indicates several concordant observations (including large case series and studies) that are not attributable to considered biases, or a general consensus among experts. "Possible" indicates as association based on case series, registries, or expert opinions. "Unlikely" indicates risk factors that have been proposed but have not been found to have any association from controlled studies.

A.     Drugs and Toxins

    1.     Definite

    • Aminorex
    • Fenfluramine
    • Dexfenfluramine
    • Toxic Rapeseed Oil

    2.     Very Likely

    • Amphetamines
    • L-tryptophan

    3.     Possible

    • Meta-amphetamines
    • Cocaine
    • Chemotherapeutic Agents

    4. Unlikely

    • Antidepressants
    • Oral Contraceptives
    • Estrogen Therapy
    • Cigarette Smoking

Ephedrine, Ephedra & Ma Huang - How do they work?

Ephedrine, Ephedra or Ma Huang and other products containing these extracts have according to the FDA, caused hundreds of illnesses, including heart attacks, seizures, strokes and even 15 reported deaths.  These amphetamine like compounds act as stimulants that can cause rapid or irregular heartbeats (heart arrhythmias) Ephedrines act in a similar way as that of adrenaline.  The ephedrine  dilates the bronchial muscles, contacts the nasal mucosa, raises the blood pressure and is a cardiac stimulant.  Further these compounds often cause psychological side effects such as depression, nervousness, insomnia, and rapid heart rate.  When taken in combination with caffeine, ephedrine can over-stimulate the central nervous system, leading to potentially life-threatening results.

TEXAS EPHEDRA PPH LAWSUIT

Currently the Willis Law Firm is representing a 42 year old Texas woman and her family after she was diagnosed with Primary Pulmonary Hypertension (PPH). After a thorough investigation of her medical background, dietary supplement, and pharmaceutical history, it was determined that the ephedra (ephedrine) from a number of dietary and nutritional supplements, was the likely cause of her primary pulmonary hypertension. The amphetamine like structure of the ephedrine alkaloid is the primary medical link. The client's medical doctors also agree that her PPH is linked to her ephedra usage. Litigation is currently pending. (March 2004)

ALABAMA -PPH EPHDREA LAWSUIT

The Willis Firm is also representing a 41 year old Alabama woman and her family after she was also diagnosed with PPH. This woman also had never consumed any of the diet pills known as Fen Phen, Pondimin or Redux.She had however taken Phentermine and a number of different herbal diet and energy supplements that contained ephedra. (Litigation is also Pending at this time - Mar 2004)

LEGAL OPTIONS FOR EPHEDRA USERS WITH PPH

ephedra,PPH,cause,primary pulmonary hypertension,ephedra, phentermine, ephedra,PPH, ephedrine,ma huang, does ephedra cause pph, metabolife pph,pulmonary hypertension,pph causes, fastin, cause,dietary,amphetamine,nutritional herbal,supplements,link,medical,legal,lawyerIf you or a loved one have been diagnosed with Primary Pulmonary Hypertension (PPH), then you may have a right to file a individual legal action against the manufacturers of the diet pills or others. Due to the nature of this serious and devastating disease process, PPH patients are urged to contact an attorney immediately after he or she has been informed of their Primary Pulmonary Hypertension diagnosis. Many important legal issues need to be addressed early after a PPH diagnosis, that can affect the outcome of the PPH litigation. Call us for a Free Confidential Consultation. Talk with a Board Certified Personal Injury Trial Lawyer about your legal rights of a PPH claim against the diet drug industry and others. No Fees or Expenses Charged unless we make a Recovery for You. 

Call Us Toll Free at 1-800-883-9858 or 1-800-468-4878 or E-mail us your questions on Free Case Evaluation Form.

 


PPH LAWYER

Primary Pulmonary Hypertension (PPH) Legal Assistance LawyerIf you or a loved one took diet drugs and recently have been given a diagnosis of Primary Pulmonary Hypertension (PPH), idiopathic pulmonary hypertension, pulmonary arterial hypertension, PAH or pulmonary hypertension, then call us for a Free PPH Lawsuit Consultation. Talk to a Personal Injury Trial Lawyer with over 20+ years of product liability trial experience that understands the complications of PPH, legal options for patients with PPH and diet drug related PPH lawsuits and litigation.

Since 1997, we have aggressively represented PPH patients in diet drug lawsuits against the makers of Fen -Phen, Redux and PPH lawsuits against the nutritional supplement industry on herbal ephedrine / ephedra / ma huang PPH lawsuits. Get PPH Lawsuit Help. Talk to a PPH Attorney now. Call Toll Free 1-800-883-9858 or E-mail us.

Primary Pulmonary Hypertension (PPH) Legal Assistance Lawyer

BOARD CERTIFIED

Primary Pulmonary Hypertension (PPH) Legal Assistance LawyerIf you have been diagnosed with PPH then it very important that you talk with an attorney. Mr. Willis is a Board Certified Personal Injury Trial Lawyer, certified by the Texas Board of Legal Specialization since 1988. No Fees or Court Costs or Expenses charged to the client unless we obtain a recovery for you. We never send you a bill for our services! Call us if you have a question.

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