Avandia and PPH - Is it Worth the Risks?
Avandia is a widely prescribed diabetic drug used to help patients with type II diabetes control blood sugar levels. Recently however, medical studies have surfaced that indicate risks for serious heart failure, and possibly PPH-primary pulmonary hypertension. PPH is a rare condition that causes the narrowing of blood vessels and consequently high blood pressure. PPH is also called primary arterial hypertension or PAH.
Avandia Black Box Warning – Heart Failure & PPH
FDA has requested a black box warning for the labels of the type 2 diabetes medications Avandia, manufactured by GlaxoSmithKline, and Actos, manufactured by Takeda Pharmaceuticals, because of increased risk for congestive heart failure associated with Avandia and Actos. FDA last month issued a public safety warning about Avandia in response to a study published on the New England Journal of Medicine Web site. The Avandia study found that 86 participants who took Avandia experienced a heart attack, compared with 72 of those who did not take the medication, a statistically significant 43% increased risk. In addition, the FDA Avandia study also found that 39 participants who took Avandia died from cardiovascular events, compared with 22 of those who did not take the medication, an almost statistically significant 64% increased risk.
Increased Risk of PPH with Avandia
FDA and GlaxoSmithKline, disclosed that, according to a meta-analysis of previous studies conducted by the company in August 2006, participants who took Avandia had a 31% increased risk for cardiovascular events. However, FDA did not take regulatory action on Avandia because of clinical trial data submitted to the agency last August. In June 2007, the FDA ordered GlaxoSmithKline to add a black box warning to Avandia's label alerting consumers and medical professionals of the increased risk of heart failure. PPH is considered a precursor to heart failure, and early PPH symptoms are usually hard to recognize, therefore an accurate diagnosis of PPH in Avandia users is often missed or delayed. Any Avandia user that has started to experience any of these common PPH symyptoms listed below, should consult a doctor and get tested for PPH.
Common Symptoms of PPH
- Extreme fatigue
- Dizziness, weakness
- Loss of consciousness
- Bluish coloring of the skin or lips
- Shortness of breath, even with moderate exertion
- Chest pain
- Fluid retention / swelling of ankles and legs
Avandia PPH Lawsuit -Talk to an Attorney
If you or a loved one have used Avandia to treat type 2 diabetes and you have been diagnosed with heart failure or Primary Pulmonary Hypertension then you may have the legal rights as to a Avandia PPH lawsuit against the makers of Avandia, GlaxoSmithKline. Please call our offices in Houston, Texas and discuss your Avandia -Primary Pulmonary Hypertension lawsuit with us. Talk to a Board Certified Personal Injury Trial Lawyer, certified by the Texas Board of Legal Specialization since 1988. Due to the statute of limitations that apply to each case, it is important that you discuss you unique facts with an attorney that understands products liability case law and that is experienced in handling PPH cases caused by diet drugs, herbal remedies, nutritional supplements and other drug complications such as Avandia.
Call Toll Free 1-800-883-9858 to speak to a lawyer about your potential Heart Failure / PPH Avandia Lawsuit or CLICK HERE